Journey
I am a researcher dedicated to decoding the architecture of life to solve critical challenges in human disease.
My work stands at the intersection of medicine, structural biology, protein engineering, and genomics. I aim to bridge the gap between atomic-level protein dynamics and clinical outcomes, bringing a unique physician-scientist perspective to every project.
Beyond my own research, I am committed to academic leadership and mentorship, fostering a collaborative environment where new ideas (and new researchers) can thrive. My goal is not just to understand molecular mechanisms, but to translate them into innovative therapeutic strategies.
Impact & Output
Global Recognition. Featured in Google DeepMind’s AlphaFold: Five Years of Impact blog by Nobel laureates Demis Hassabis and John Jumper.
30+ Submitted Research Papers. First-author publications in journals such as Pharmaceutical Research (cover article, 2024), PLoS ONE, and Journal of Molecular Evolution, with additional manuscripts under review in top-journals.
International High-impact Conference Presentations such as SfN Neuroscience 2025, European Human Genetics Conference 2025, Nature conferences: AI for Discovery and Research Automation)
3 Patent Applications & Several Awards (including the Dean's Award for Scientific Excellence, and EAN conference grant)
Technical Expertise
Core Competencies
Macromolecule Structure & Design: Ab initio modeling, structural topology, molecular mimicking, and MD simulations for both globular and membrane proteins.
Genomics & Evolution: Ancestral protein reconstruction, large-scale variant analysis, alternative splicing, and signal transduction pathways.
Mathematical Biology: Pioneering the application of Game Theory and Extensive Form Structures to genomic evolution, toolkit design, bioinformatics.
Medical Neuroscience & Immunology: Systems-level analysis of neurodegenerative pathways, immune modulation, and clinical disease mechanisms.
Methodological Toolkit
. Ab initio structure prediction, Homology modeling, QTY-variant design, Oligomer assembly prediction. Molecular Dynamics (MD), Membrane distortions, Lipid-protein interactions. Binding & Energetics, MMGBSA / MMPBSA free energy calculations, Ligand docking. Causality: Kernel causality algorithms, Confounding variable resolution. Correlation: Partial Spearman correlations, Residue co-evolution analysis. Theory: Game Theory applications, Evolutionary stability models. Evolutionary Analysis: Shannon Entropy, Purifying selection modeling, Ancestral Sequence Reconstruction (ASR). Variant Profiling: Mutational pathways, Splice-altering variation analysis. Development: Toolkit Development, Clinical Database Architecture. Wet Lab: In vitro, Assays, Protein biochemistry. Clinical Skills: Physical Examination, Patient Communication, Medical History Taking. Translational: Bridging molecular data with clinical phenotypes.
Recent experience
2022 Aug - current
Massachusetts Institute of Technology
Research Collaborator - Part Time
Laboratory of Molecular Architecture, Media Lab
> Isoforms and alternative mRNA splicing of neurotransmitter transporters
> Heteromerization and contemporary modulator design
> MSA-based protein structure prediction and computational analysis
> Extensive form games and ESS aplications in molecular events
> Structural topology and alpha helices of neuronal transporters
> Evolutionary Profiling and Natural variants analysis,
> Protein Secondary Structure Assignment, Helical structure analysis in neuronal transporter proteins
2023 Sept - 2024 Jan
University College London
Research Collaborator - Part Time
Structural Immunology Group - UCL
> Alternative mRNA splicing and structural alterations in coagulation factors
> Mutational dynamics and epistasis in disease evolution
> Phenotypical profiling and structural prediction
2023 Jan- Aug
University College London Hospitals NHS Foundation Trust
Guest Scientist - Full Time Visitor
visitor at UCL Medical School
> Evolutionarily-related proteins in Homo sapiens (Human)
> Genetic variants analysis and molecular mechanisms of related diseases
> Protein Structural Assessment of the effects of genetic variants
> Alternative splicing, and mRNA processing
> Database design with MySQL and HTML programming
